Connecting European Cohorts to Increase Common and Effective Response to SARS-CoV-2 Pandemic
Keyvisual image main

ORCHESTRA is developing a networked platform for sharing data and for creating a new large-scale, pan-European cohort for research on the SARS-CoV-2 pandemic, providing a model for addressing future public health threats.

The aim of the ORCHESTRA (Connecting European Cohorts to Increase Common and Effective Response to SARS-CoV-2 Pandemic) project is the creation of a new large-scale pan-European cohort, in order to significantly improve responsiveness to SARS-CoV-2 and provide a model for responsiveness for new public health threats.

ORCHESTRA provides an innovative approach to learn from the pandemic SARS-CoV-2 crisis and derive recommendations to be better prepared in case of a further waves and future pandemics. The ORCHESTRA project aims to deliver sound scientific evidence for the prevention and treatment of the infections caused by SARS-CoV-2 assessing epidemiological, clinical, microbiological, and genotypic aspects of population, environment and socio-economic features. The project builds up on existing and new large scale population cohorts in Europe (France, Germany, Spain, Italy, Belgium, Romania, Netherlands, Portugal, Luxemburg, and Slovakia) and non-European countries (India, Peru, Ecuador, Colombia, Venezuela, Argentina, Brazil, Congo, and Gabon) including SARS-CoV-2 infected and non-infected individuals of all ages and conditions. The main outcome of ORCHESTRA is the creation of a new pan-European cohort applying homogenous protocols for data collection, data sharing, sampling, and follow up, which can rapidly advance the knowledge on the control and management of the COVID-19. ORCHESTRA will also include SARS-CoV-2-negative individuals and thereby enable a prospective follow-up and an analysis of vaccination response when vaccines will be available. The new ORCHESTRA platform responds thus to an urgent need and provides a rapid and coordinated solution to protect the general populations and deliver the best care to affected individuals.

The High-Performance Computing Center Stuttgart (HLRS) will contribute its expertise in research data management, big data and data engineering to ORCHESTRA. Within the project, HLRS helps to build the federated research architecture for cohort analysis based on three layers: National Data Providers, National Hubs and the centralized Orchestra Portal. The HLRS will lead the implementation of the National hubs throughout the project partners and act as the National Hub in Germany for the cohort data. Moreover the HLRS be participating in the design and implementation of the ORCHESTRA portal platform.


01. December 2020 -
30. November 2024


EU Horizon 2020, ERAvsCORONA Action Plan

Project partners

  • Università degli studi di Verona, Italy
  • Alma Mater studiorum - Università di Bologna, Italy
  • Institut National De La Sante Et De La Recherche Medicale, France
  • Servicio Andaluz de Salud, Spain
  • CINECA Consorzio interuniversitario, Italy
  • Luxembourg Institute of Health, Luxemburg
  • Assistance Publique - Hôpitaux de Paris, France
  • Regione Emilia Romagna - Agenzia Sanitaria e Sociale, Italy
  • Fundacion privada instituto de salud GLOBAL BARCELONA, Spain
  • Ludwig-Maximilians-Universität München, Germany
  • Universiteit Antwerpen, Belgium
  • Helmholtz Zentrum München Deutsches Forschungzentrum Gesundheit Und Umwelt Gmbh, Germany
  • University Hospital of Cologne - Klinikum der Universität zu Köln, Germany
  • Fondation Congolaise pour la Recherche Médicale, Congo
  • University of Stuttgart - The High Performance Computing Center (USTUTT) - Germany, Germany
  • Centre de Recherches Médicales de Lambaréné, Gabon
  • Regional Authority of Public Health Banska Bystrica, Slovak Republic
  • Berliner Institut für Gesundheitsforschung Körperschaft des öffentlichen Rechts,Germany
  • Academisch Ziekenhuis Groningen, The University Medical Center Groningen, Netherland
  • Centre Informatique National De L’Enseignement Superior, France
  • Hospital Beatriz Ângelo - GLSMED Learning Health Hospital Beatriz Ângelo, Portugal
  • Universidad de Oviedo, Spain
  • Hospital General de Agudos Carlos G Durand, Argentina
  • National Institute of Public Health, Romania
  • Universitätsklinikum Heidelberg, Germany
  • Translational Health Science and Technology Institute, India
  • Catholics Bishops Conference of India, Society for Medical Education


Eu Logo: Funded by the European Union